A differentiated approach to dissaggregate
existing amyloid-β plaque

Filamentous phage bind to and dissaggregate Aβ aggregates as demonstrated in numerous in vitro and in vivo experiments.

Phage bind to Aβ aggregates and
break them apart

Once dissaggregated, amyloid protein and phage are cleared

Vehicle control	Phage
Statistically significant Aβ plaque reduction after single, intracranial injection in transgenic mouse

Additional work shows similar effect on other neural aggregates.